Welcome to 3TRNS Lab
(Temporal, Theoretical, Translational Research And Neural Stimulation Lab) in Clinical Psychology PhD Program at University of Connecticut
In addition to the profound emotional cost to families, the economic cost of schizophrenia in the US alone was estimated at $155.7 billion for 2013 (Cloutier et al., 2016); therefore, our primary line of research is dedicated to advance our understanding of the etiology of schizophrenia, as well as informing possible pharmacological treatments and novel interventions for cognition and functional performance. This line of inquiry cuts across the fields of clinical neuropsychology, psychiatry, neuroscience, and neurology, and also has implications for developing pharmacological treatments. Our ultimate research goal is to translate physiological knowledge into treatments for neuropsychological disorders.
Examples of our current research projects are: (1) using MRI techniques (fMRI, DTI), EEG, and transcranial magnetic stimulation (TMS) to investigate neural oscillations and auditory sensory processing in healthy participants and patients with schizophrenia at the Olin Neuropsychiatry Research Center of Hartford Hospital, (2) investigating the effect of acute administration of ketamine on glutamate, GABA, and neuronal oscillations in healthy participants (simultaneous MRS-EEG recordings), (3) using machine-learning models to identify “optimal” neural oscillatory patterns from high definition scalp EEGs for cognitive functions and computer-assisted (i.e., brain-computer interface) cognitive remediation programs in healthy participants and patients with schizophrenia, (4) investigating the normal patterns of EEGs in healthy participants while they are performing the jitter orientation visual integration task.
Please see our PROJECTS page for details of studies.