Welcome to 3TRNS Lab* at UConn
*pronounce “3 turns lab”
Temporal, Theoretical, Translational Research and Neural Stimulation Lab at University of Connecticut
Our lab is interested in translating neurophysiological knowledge into interventions for neurological and psychiatric disorders. We are interested in conducting research that will aid in developing and translating advanced neurophysiological knowledge into novel treatments for medication-resistant schizophrenia. Specifically, we hope to test interventions and new chemical compounds to ameliorate pathological neural oscillations in schizophrenia.
Examples of our current research projects are: (1) using MRI techniques (fMRI, DTI), EEG, and transcranial magnetic stimulation (TMS) to investigate neural oscillations and auditory sensory processing in healthy participants and patients with schizophrenia at the Olin Neuropsychiatry Research Center of Hartford Hospital, (2) investigating the effect of acute administration of ketamine on glutamate, GABA, and neuronal oscillations in healthy participants (simultaneous MRS-EEG recordings), (3) using machine-learning models to identify “optimal” neural oscillatory patterns from high definition scalp EEGs for cognitive functions and computer-assisted (i.e., brain-computer interface) cognitive remediation programs in healthy participants and patients with schizophrenia, (4) investigating relationships among neurotransmitters, neural oscillations, and behaviors in patients with OCD (5) and individuals with reading disability.